1397258-00-2

Upstream product

• 296238-70-5 N-benzyloxycarbonyl-2,2,2-trifluoroacetimidoyl chloride 

Downstream Products

• 1597414-44-2 methyl 3-(4-chlorophenyl)-2-oxo-4-(2-oxopropyl)-6-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 1597414-45-3 methyl 1-(4-chlorophenyl)-2-oxo-4-(2-oxopropyl)-4-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate 

Relevant academic research and scientific papers

Heterocyclization of N-(1-chloro-2,2,2-trifluoroethylidene)carbamates with β-enaminoesters - A novel synthetic strategy to functionalized trifluoromethylated pyrimidines

A novel synthetic strategy to 4-trifluoromethyl substituted 2-oxo-1,2-dihydropyrimidine-5-carboxylates has been developed based on the cyclocondensation of β-enaminoesters with N-(1-chloro-2,2,2- trifluoroethylidene)carbamates.