139751-00-1

Upstream product

• 139750-99-5 (1R,2S,6R,7S)-4-But-3-ynyl-5-methoxy-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-3-one 
• 882-33-7 diphenyldisulfane 
• 139750-90-6 (1R,2S,5R/S,6R,7S)-(+)-4-(but-3'-ynyl)-5-hydroxy-4-azatricyclo<5.2.1.0^2,6>dec-8-en-3-one 

Downstream Products

• 3348-73-0 (+)-laburnine 
• 139751-01-2 S-phenyl (1S,2R,3R,4S,9S,10R)-(+)-8-oxo-7-azatetracyclo<8.2.1.0^2,9.0^3,7>tridec-11-ene-4-carbothioate 

Relevant academic research and scientific papers

A Novel Approach to Bicyclic Alkaloids Using a Tandem Diastereoselective Acyliminocyclization and Retro Diels-Alder Reaction Sequence. Synthesis of (+)-Indolizidine and (+)-Laburnine

A new aproach to diastereoselective cationic cyclization by stereocontrol due to the bicycloheptene moiety in a chiral γ-hydroxy lactam is described.The diastereoselective reaction followed by Diels-Alder cycloreversion has ben succesfully applied to a chiral synthesis of (+)-indolizidine and (+)-laburnine (=trachelanthamidine).