139773-03-8Relevant articles and documents
Acyl CoA:cholesterol acyltransferase (ACAT) inhibitors: Synthesis and structure-activity relationship studies of a new series of trisubstituted imidazoles
Higley,Wilde,Maduskuie,Johnson,Pennev,Billheimer,Robinson,Gillies,Wexler
, p. 3511 - 3522 (2007/10/02)
A series of 4,5-diaryl-2-(substituted thio)-1H-imidazoles has been synthesized and demonstrated to be potent inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). The design, synthesis, and structure-activity relationships for this series are reporte