139773-07-2Relevant academic research and scientific papers
INDOLE DERIVATIVES
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, (2008/06/13)
Specific 6-substituted or 2-alkyl substituted indole or 2,3-dihydroindole compounds are provided, having long lasting serotonin activity with specific binding to 5-HT 2 receptors of the central nervous system. These compounds are suitable for therapeutic treatment of CNS disorders, such as anxiety, depression, sleep disturbances, migraine, negative symptoms of schizophrenia, and Parkinson's disease.
Selective, Centrally Acting Serotonin 5-HT2 Antagonists. 1. 2- and 6-Substituted 1-Phenyl-3-(4-piperidinyl)-1H-indoles
Perregaard, Jens,Andersen, Kim,Hyttel, John,Sanchez, Connie
, p. 4813 - 4822 (2007/10/02)
A series of 1-ethyl>-2-imidazolidinones has been synthesized. The 1-position of the indole is substituted with phenyl groups and in the 2- or 6-positions are additional substituents. An analogous series with the imidazo
