139774-25-7

Basic information

• Product Name: 4-fluorophenyl-1H-indole-2-carboxylic acid
• Synonyms: 4-fluorophenyl-1H-indole-2-carboxylic acid
• CAS NO: 139774-25-7
• Molecular Formula: C₁₅H₁₀FNO₂
• Molecular Weight: 255
• Mol File: 139774-25-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-fluorophenyl-1H-indole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-fluorophenyl-1H-indole-2-carboxylic acid(139774-25-7)
• EPA Substance Registry System: 4-fluorophenyl-1H-indole-2-carboxylic acid(139774-25-7)

Safety Data

• Hazardous Substances Data: 139774-25-7(Hazardous Substances Data)

Upstream product

• 1477-50-5 Indole-2-carboxylic acid 
• 352-34-1 4-fluoro-1-iodobenzene 
• 352-33-0 1-Chloro-4-fluorobenzene 

Downstream Products

• 139774-26-8 1-(4-fluorophenyl)-2-(hydroxymethyl)-1H-indole 
• 139774-02-0 1-<2-<4-<1-(4-fluorophenyl)-2-methyl-1H-indol-3-yl>-1,2,3,6-tetrahydropyridin-1-yl>ethyl>-2-imidazolidinone 
• 139774-01-9 1-(4-fluorophenyl)-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole 
• 139774-24-6 1-(4-fluorophenyl)-2-methyl-1H-indole 

Relevant articles and documents

L -(-) -Quebrachitol as a Ligand for Selective Copper(0)-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles

l-(-)-Quebrachitol (QCT) has been found as a ligand of copper powder for selective N-arylation of nitrogen-containing heterocycles with aryl halides. Furthermore, another potential catalytic system (copper powder/QCT/t-BuOK) was successfully adapted to unactivated aryl chlorides.

INDOLE DERIVATIVES

Specific 6-substituted or 2-alkyl substituted indole or 2,3-dihydroindole compounds are provided, having long lasting serotonin activity with specific binding to 5-HT 2 receptors of the central nervous system. These compounds are suitable for therapeutic treatment of CNS disorders, such as anxiety, depression, sleep disturbances, migraine, negative symptoms of schizophrenia, and Parkinson's disease.