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Colocynthin, a toxic glucoside compound, is found in the bitter apple or desert gourd plant, Citrullus colocynthis. Known for its potent laxative and purgative properties, it has been traditionally used for treating constipation and digestive issues. However, due to its toxic nature, which can lead to adverse effects such as nausea, vomiting, diarrhea, and abdominal pain, its use in modern medicine has been discontinued in favor of safer alternatives.

1398-78-3

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1398-78-3 Usage

Uses

Used in Traditional Medicine:
Colocynthin was traditionally used as a laxative and purgative agent for treating constipation and other digestive disorders. Its strong purgative properties made it effective in clearing the bowels, but its toxic nature and potential for adverse effects have led to its discontinuation in modern medicine.
Used in Pharmaceutical Research:
Although not currently used in modern medicine, the study of colocynthin's properties may contribute to the development of new pharmaceutical compounds with better safety profiles and targeted effects. Research into its mechanism of action and potential applications could lead to the discovery of safer alternatives for treating digestive disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 1398-78-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,9 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1398-78:
(6*1)+(5*3)+(4*9)+(3*8)+(2*7)+(1*8)=103
103 % 10 = 3
So 1398-78-3 is a valid CAS Registry Number.
InChI:InChI=1/C38H54O13/c1-18(40)51-33(2,3)13-12-25(42)38(9,48)30-21(41)15-35(6)24-11-10-19-20(37(24,8)26(43)16-36(30,35)7)14-22(31(47)34(19,4)5)49-32-29(46)28(45)27(44)23(17-39)50-32/h10,12-14,20-21,23-24,27-30,32,39,41,44-46,48H,11,15-17H2,1-9H3/b13-12+/t20-,21-,23-,24+,27-,28+,29-,30+,32?,35+,36-,37+,38+/m1/s1

1398-78-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name [(E,6R)-6-hydroxy-6-[(8S,9R,10R,13R,14S,16R,17R)-16-hydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-2-methyl-5-oxohept-3-en-2-yl] ace

1.2 Other means of identification

Product number -
Other names EINECS 215-745-9

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1398-78-3 SDS

1398-78-3Upstream product

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