1398057-45-8Relevant articles and documents
Reaction between 4-Nitro-1,3-diarylbutan-1-ones and Ammonium Acetate in the Presence of Morpholine and Sulfur: An Efficient Synthesis of 2,4-Diarylpyrroles
Adib, Mehdi,Ayashi, Neda,Heidari, Fatemeh,Mirzaei, Peiman
, p. 1738 - 1742 (2016/07/06)
An efficient synthesis of 2,4-diarylpyrroles is described. Heating a mixture of a 4-nitro-1,3-diarylbutan-1-one and ammonium acetate in the presence of morpholine and sulfur afforded the corresponding 2,4-diarylpyrroles in excellent yields.
2,4- vs 3,4-disubsituted pyrrole synthesis switched by copper and nickel catalysts
Chen, Feng,Shen, Tao,Cui, Yuxin,Jiao, Ning
supporting information, p. 4926 - 4929,4 (2012/12/12)
A novel and efficient copper or nickel catalyzed highly selective denitrogenative annulation of vinyl azides with aryl acetaldehydes has been developed. 2,4- and 3,4-diaryl substituted pyrroles, which are difficult to synthesize by the reported methods, can be highly regioselectively prepared by this protocol simply switched by the selection of the transition metal catalysts. Compared with the reported acidic or basic conditions for polysubstituted pyrrole synthesis, the present reaction conditions are mild, neutral, and very simple without any additives.