1398243-08-7Relevant academic research and scientific papers
Highly enantioselective Friedel-Crafts alkylation of indoles and pyrrole with β,γ-unsaturated α-ketoesters catalyzed by heteroarylidene-tethered bis(oxazoline) copper complexes
Liu, Lei,Ma, Hongli,Xiao, Yumei,Du, Fengpei,Qin, Zhaohai,Li, Nan,Fu, Bin
, p. 9281 - 9283 (2012)
The simple and cheap chiral catalyst, heteroarylidene-tethered Ph-bis(oxazoline)-Cu(OTf)2, can efficiently catalyze the asymmetric F-C alkylation of indoles and pyrrole with β,γ-unsaturated α-ketoesters. The 3-indolyl adducts were obtained in u
