139887-98-2 Usage
General Description
Uridine, 2',3',5'-trideoxy-5'-oxo-, also known as Uridine Triacetate, is a synthetic source of uridine used for the treatment of hereditary orotic aciduria. It is an orally administered prodrug of uridine, which is vital for the biosynthesis of pyrimidine nucleotides and plays a crucial role in cellular metabolism. Uridine Triacetate serves as a rescue therapy for patients with hereditary orotic aciduria, a rare genetic disorder characterized by the inability to synthesize uridine. By providing exogenous uridine, Uridine Triacetate helps to restore the deficiency and improve the symptoms associated with the condition.
Check Digit Verification of cas no
The CAS Registry Mumber 139887-98-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,8,8 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 139887-98:
(8*1)+(7*3)+(6*9)+(5*8)+(4*8)+(3*7)+(2*9)+(1*8)=202
202 % 10 = 2
So 139887-98-2 is a valid CAS Registry Number.
139887-98-2Relevant articles and documents
Synthesis of 4'-cyanothymidine and analogs as potent inhibitors of HIV
O-Yang,Wu,Fraser-Smith,Walker
, p. 37 - 40 (1992)
4'-Cyanothymidine inhibits HIV in A301 (Alex) cells with an IC50 of 0.002 μM. The uridine and cytidine analogs show similar potencies.
