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BAPTA-AM, a lipophilic diester of BAPTA, is a compound utilized in various applications due to its ability to inhibit proteolytic activities of specific metalloproteinases, such as calpain and TACE. It is characterized by its fluorescence properties, with a maximum absorption at 287nm and an extinction coefficient of 5.9 x 10^-3.

139890-68-9

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139890-68-9 Usage

Uses

Used in Pharmaceutical Industry:
BAPTA-AM is used as an inhibitor for proteolytic activities of certain metalloproteinases, such as calpain and TACE, for the purpose of studying and potentially treating conditions related to these enzymes' dysregulation.
Used in Research Applications:
BAPTA-AM is used as a research tool to investigate the roles of metalloproteinases, calpain, and TACE in various biological processes and diseases. Its fluorescence properties allow for easy monitoring and tracking of these enzymes in experimental settings.
Used in Drug Development:
BAPTA-AM serves as a starting point for the development of new drugs targeting metalloproteinases, calpain, and TACE, which may have therapeutic potential in treating conditions associated with the dysregulation of these enzymes.

Check Digit Verification of cas no

The CAS Registry Mumber 139890-68-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,8,9 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 139890-68:
(8*1)+(7*3)+(6*9)+(5*8)+(4*9)+(3*0)+(2*6)+(1*8)=179
179 % 10 = 9
So 139890-68-9 is a valid CAS Registry Number.
InChI:InChI=1/C25H28N2O12/c1-17(28)38-16-39-25(35)15-27(14-24(33)34)19-7-3-5-9-21(19)37-11-10-36-20-8-4-2-6-18(20)26(12-22(29)30)13-23(31)32/h2-9H,10-16H2,1H3,(H,29,30)(H,31,32)(H,33,34)

139890-68-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[2-[2-[2-[[2-(acetyloxymethoxy)-2-oxoethyl]-(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:139890-68-9 SDS

139890-68-9Upstream product

139890-68-9Downstream Products

139890-68-9Related news

Uncovering malathion (an organophosphate insecticide) action on Ca2+ signal transduction and investigating the effects of BAPTA-AM (cas 139890-68-9) (a cell-permeant Ca2+ chelator) on protective responses in glial cells07/15/2019

Malathion, one of commonly used organophosphate insecticides, has a wide range of toxic actions in different models. However, the effect of this compound on Ca2+ homeostasis and its related cytotoxicity in glial cells is elusive. This study examined whether malathion evoked intracellular Ca2+ co...detailed

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