Helleborein is a toxic compound found in various species of the Helleborus plant, belonging to the Ranunculaceae family. It is known for its potent cardiotoxic effects, causing symptoms such as vomiting, diarrhea, and convulsions in animals and humans upon ingestion. Helleborein primarily acts by disrupting the normal functioning of sodium and potassium channels in the heart muscle, leading to arrhythmias and potentially fatal cardiac arrests.
1399-70-8
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Basic information
- Product Name: HELLEBOREIN)
- Synonyms: Helleborein; Caswell No. 473; EPA Pesticide Chemical Code 002001; Hellebore alkaloids; Helleborin
- CAS NO:1399-70-8
- Molecular Formula: C37H56 O18
- Molecular Weight: 788.84
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: HELLEBOREIN)(CAS DataBase Reference)
- NIST Chemistry Reference: HELLEBOREIN)(1399-70-8)
- EPA Substance Registry System: HELLEBOREIN)(1399-70-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- RIDADR: 1544
- WGK Germany:
- RTECS:
- HazardClass: 6.1(a)
- PackingGroup: II
- Hazardous Substances Data: 1399-70-8(Hazardous Substances Data)
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1399-70-8 Usage
Uses
Used in Traditional Medicine:Helleborein has historically been used as a poison and as a purgative in traditional medicine. However, its use is now largely discouraged due to the high risk of adverse effects.
Used in Research:
Due to its potent cardiotoxic effects, helleborein is used in research settings to study the effects of toxins on the heart and to develop potential treatments for arrhythmias and other cardiac conditions. This research is conducted under strict safety protocols to minimize the risk of exposure to the toxic compound.
Check Digit Verification of cas no
The CAS Registry Mumber 1399-70-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,9 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.Calculate Digit Verification of CAS Registry Number 1399-70:
(6*1)+(5*3)+(4*9)+(3*9)+(2*7)+(1*0)=98
98 % 10 = 8
So 1399-70-8 is a valid CAS Registry Number.
1399-70-8Upstream product
1399-70-8Downstream Products
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