139908-33-1

Basic information

• Product Name: 2-Pyridinamine,6-ethyl-3-methyl-(9CI)
• Synonyms: 2-Pyridinamine,6-ethyl-3-methyl-(9CI)
• CAS NO: 139908-33-1
• Molecular Formula: C8H12N2
• Molecular Weight: 136.19428
• Product Categories: PYRIDINE
• Mol File: 139908-33-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinamine,6-ethyl-3-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinamine,6-ethyl-3-methyl-(9CI)(139908-33-1)
• EPA Substance Registry System: 2-Pyridinamine,6-ethyl-3-methyl-(9CI)(139908-33-1)

Safety Data

• Hazardous Substances Data: 139908-33-1(Hazardous Substances Data)

Upstream product

• 139908-25-1 2-Methyl-5-oximinoheptanenitrile 
• 146331-16-0 N-(6-Ethyl-3-methyl-pyridin-2-yl)-acetamide 
• 107-12-0 propiononitrile 
• 74-86-2 acetylene 

Relevant articles and documents

Synthesis of 6-Substituted 2-(N-Acetylamino)pyridines and 2-Aminopyridines by Cyclization of 5-Oximinoalkanenitriles

Oxime derivatives of 5-oxoalkanenitriles (C6 chain or longer) were cyclized in most cases with a combination of AcCl and Ac2O, or Ac2O and HCl to 6-substituted 2-(N-acetylamino)pyridines.Alkaline hydrolysis gave the corresponding 2-aminopyridines in overall yields of 40-65 percent, with the exception of pyridine 3e.Oxime derivatives of 5-oxopentanenitriles did not cyclize but gave glutaronitriles instead.In some experiments with 5-oximinohexanenitrile (1a), 2,4-dimethyl-5-(2-cyanoethyl)oxazole (9) was detected in addition to the main product, 2-(N-acetylamino)-6-methylpyridine (2a).Formation of these compounds can be explained on the basis of a common intermediate 7 formed through rearrangement of the O-acetylated 5-oximinohexanenitrile (4).