139909-17-4

Basic information

• Product Name: Pyrrolidine, 1-(3-fluorophenyl)-
• Synonyms: Pyrrolidine, 1-(3-fluorophenyl)-;1-(3-fluorophenyl)Pyrrolidine
• CAS NO: 139909-17-4
• Molecular Formula: C10H12FN
• Molecular Weight: 165.2073832
• Mol File: 139909-17-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrrolidine, 1-(3-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 1-(3-fluorophenyl)-(139909-17-4)
• EPA Substance Registry System: Pyrrolidine, 1-(3-fluorophenyl)-(139909-17-4)

Safety Data

• Hazardous Substances Data: 139909-17-4(Hazardous Substances Data)

Usage

General Description

Pyrrolidine, 1-(3-fluorophenyl)- is a chemical compound with a pyrrolidine ring and a fluoro-substituted phenyl group. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Pyrrolidine, 1-(3-fluorophenyl)- has been reported to exhibit antifungal and antibacterial activity, making it a potential candidate for the development of new drugs. In addition, its unique chemical structure and reactivity make it suitable for use in various organic synthesis reactions, including the formation of heterocyclic compounds. However, as with any chemical compound, proper handling and safety precautions should be taken when working with Pyrrolidine, 1-(3-fluorophenyl)- to minimize the risk of adverse effects on human health and the environment.

Upstream product

• 123-75-1 pyrrolidine 
• 372-18-9 1,3-Difluorobenzene 
• 625-98-9 3-chlorofluorobenzene 
• 110-52-1 1,4-dibromo-butane 
• 372-19-0 meta-fluoroaniline 

Relevant articles and documents

Catalytic Asymmetric Arylation of α-Aryl-α-diazoacetates with Aniline Derivatives

The asymmetric arylation of diazo compounds with aniline derivatives cooperatively catalyzed by an achiral dirhodium complex and a chiral spiro phosphoric acid is reported. The reaction provides a new method for the facile synthesis of α-diarylacetates, v

Organic photoredox catalytic α-C(sp3)-H phosphorylation of saturated: Aza -heterocycles

A metal-free C(sp3)-H phosphorylation of saturated aza-heterocycles via the merger of organic photoredox and Br?nsted acid catalyses was established under mild conditions. This protocol provided straightforward and economic access to a variety of valuable α-phosphoryl cyclic amines by using commercially available diarylphosphine oxide reagents. In addition, the D-A fluorescent molecule DCQ was used for the first time as a photocatalyst and exhibited an excellent photoredox catalytic efficiency in this transformation. A series of mechanistic experiments and DFT calculations demonstrated that this transformation underwent a sequential visible light photoredox catalytic oxidation/nucleophilic addition process.

N-Heterocyclic carbene-palladacyclic complexes: synthesis, characterization and their applications in the C-N coupling and α-arylation of ketones using aryl chlorides

N-Heterocyclic carbene-palladacyclic complexes 3 were successfully achieved in a one-pot procedure under mild conditions. The structure of 3a was unambiguously confirmed by X-ray single crystal diffraction and it was an active catalyst in the Buchwald-Hartwig amination and α-arylation of ketones even at very low catalyst loadings (0.01 mol%).