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Urea,N,N''-2,6-pyridinediylbis[N'-(2-chloroethyl)(9CI) is a chemical compound that combines urea and 2,6-pyridinediylbis(N'-(2-chloroethyl)). It is recognized for its alkylating properties and is utilized in the medical field, particularly in cancer treatment.

13991-70-3

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13991-70-3 Usage

Uses

Used in Oncology:
Urea,N,N''-2,6-pyridinediylbis[N'-(2-chloroethyl)(9CI) is used as a chemotherapeutic agent for the treatment of various cancers. It functions by disrupting the replication and transcription processes of DNA in cancer cells, leading to cell death and tumor reduction.
Used in Combination Therapies:
Urea,N,N''-2,6-pyridinediylbis[N'-(2-chloroethyl)(9CI) is often used in combination with other drugs in chemotherapy regimens to enhance the effectiveness of cancer treatment. The synergistic action of Urea,N,N''-2,6-pyridinediylbis[N'-(2-chloroethyl)(9CI) with other chemotherapeutic agents can improve patient outcomes by increasing the overall response to treatment.
Used in the Treatment of Hodgkin's Disease:
Urea,N,N''-2,6-pyridinediylbis[N'-(2-chloroethyl)(9CI) is specifically used in the treatment of Hodgkin's disease, a type of lymphoma. Its alkylating action targets the cancerous cells, contributing to the management and potential remission of the disease.
Used in the Treatment of Non-Hodgkin's Lymphoma:
In addition to Hodgkin's disease, Urea,N,N''-2,6-pyridinediylbis[N'-(2-chloroethyl)- (9CI) is also employed in the treatment of non-Hodgkin's lymphoma, demonstrating its versatility in oncological applications. The alkylating mechanism of Urea,N,N''-2,6-pyridinediylbis[N'-(2-chloroethyl)(9CI) is effective in combating the uncontrolled cell growth characteristic of lymphomas.
Caution: Due to the potential for severe side effects, such as bone marrow suppression and an increased risk of secondary malignancies, Urea,N,N''-2,6-pyridinediylbis[N'-(2-chloroethyl)(9CI) should only be administered under the supervision of a qualified healthcare professional.

Check Digit Verification of cas no

The CAS Registry Mumber 13991-70-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,9 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13991-70:
(7*1)+(6*3)+(5*9)+(4*9)+(3*1)+(2*7)+(1*0)=123
123 % 10 = 3
So 13991-70-3 is a valid CAS Registry Number.

13991-70-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-[6-(2-chloroethylcarbamoylamino)pyridin-2-yl]urea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13991-70-3 SDS

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