139926-40-2Relevant academic research and scientific papers
Synthesis, decarboxylation, and nitrosation of 1-acyl-2-pyrrolidone-3-carboxylic acids: A convenient novel entry to 2,3-dioxopyrrolidine derivatives
Gailius,Stamm
, p. 89 - 92 (2007/10/02)
Esters 1 of 1-acyl-2-pyrrolidone-3-carboxylic acids 2 were hydrolized to 2 with acetic acid/HCl at 60-70°C. Reaction of 1a with formic acid/HCl at 60-75°C led to (not isolated) 2a which began to decarboxylate to 3a during the conversion of 1a to 2a even a
