1399281-24-3

Upstream product

• 1292278-70-6 9,12-dioxa-3-azadispiro[4.2.4⁸.2⁵]tetradecan-4-one 
• 1292278-69-3 8-cyanomethyl-1,4-dioxaspiro[4.5]decane-8-carboxylic acid ethyl ester 
• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 
• 1489-97-0 ethyl 1,4-dioxaspiro[4.5]decane-8-carboxylate 
• 1399175-29-1 2-(4-((R)-2,2,2-trifluoro-1-methoxyethyl)phenyl)-2-azaspiro[4.5]decane-1,8-dione 
• 1292278-80-8 10-[4-((R)-2,2,2-trifluoro-1-hydroxy-ethyl)-phenyl]-1,4-dioxa-10-aza-dispiro[4.2.4.2]tetradecan-9-one 

Relevant academic research and scientific papers

SEC-HYDROXYCYCLOHEXYL DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2 and R3 are as described herein, compositions including the compounds and methods of using the compounds.

SEC-HYDROXYCYCLOHEXYL DERIVATIVES AS HSL INHIBITORS FOR THE TREATMENT DIABETES

The invention provides novel compounds having the general formula (I) wherein R1, R2 and R3 are as described herein, and compositions including the compounds. The use of the compounds as inhibitors of hormone sensitive lipose (HSL) for the treatment of diseases such as diabetes and metabolic symdrome is also disclosed.