1399357-78-8Relevant academic research and scientific papers
An efficient total synthesis of (-)-epothilone B
Wang, Jie,Sun, Bing-Feng,Cui, Kai,Lin, Guo-Qiang
, p. 6354 - 6357 (2012)
An efficient total synthesis of (-)-epothilone B has been achieved in ca. 8% yield over 11 steps from 9 (or 10 steps from 7/8), which features a bissiloxane-tethered ring closing metathesis reaction to approach the trisubstituted (Z) double bond and forms a new basis for further development of an industrial process for epothilone B and ixabepilone.
