139962-91-7

Upstream product

• 139982-85-7 Methyl 4-benzyloxy-2-(4-benzyloxy-2-formylphenyl)-5-methoxybenzoate 
• 139963-08-9 1-<5-Hydroxy-2-(5-hydroxy-2-methoxycarbonyl-4-methoxyphenyl)phenyl>-2-<4-hydroxy-4-(4-methoxycarbonylphenoxy)phenyl>-ethane 
• 139963-09-0 1-<5-Benzyloxy-2-(5-benzyloxy-2-methoxycarbonyl-4-methoxyphenyl)phenyl>-2-<4-benzyloxy-4-(4-methoxycarbonylphenoxy)phenyl>-ethane 
• 139963-07-8 (E)- and (Z)-1-<5-Benzyloxy-2-(5-benzyloxy-2-methoxycarbonyl-4-methoxyphenyl)-phenyl>-2-<4-benzyloxy-4-(4-methoxycarbonylphenoxy)phenyl>-ethene 
• 139963-10-3 1-<5-Benzyloxy-2-(5-benzyloxy-2-hydroxymethyl-4-methoxyphenyl)phenyl>-2-<4-benzyloxy-4-(4-hydroxymethylphenoxy)phenyl>-ethane 
• 139963-13-6 methyl 4-(benzyloxy)-2-bromo-5-methoxybenzoate 
• 139962-97-3 3-Benzyloxy-6-boronobenzaldehyde diethyl acetal 
• 139963-11-4 1-<5-Benzyloxy-2-(5-benzyloxy-2-bromomethyl-4-methoxyphenyl)phenyl>-2-<4-benzyloxy-4-(4-bromomethylphenoxy)phenyl>-ethane 

Relevant academic research and scientific papers

Total synthesis of plagiochins C, and D, macrocyclic bis(bibenzyl) constituents of plagiochila acantophylla

Plagiochins C (3) and D (4) were synthesized by convergent schemes. Rings C and B were joined by Ullman ether synthesis, the aryl-aryl bond between rings A and D was formed by Pd(0)-catalysed coupling of an arylboronic acid (ring D) and a bromobenzoic ester (ring A). Rings C and D were linked by the Wittig reaction, while final ring closure was effected by tetraphenylethene assisted Wurtz reaction.