1399654-82-0

Basic information

• Product Name: 5′-nitrospiro[cyclopropane-1,3′-indoline]-2′-one
• CAS NO: 1399654-82-0
• Molecular Weight: 204.185
• Mol File: 1399654-82-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5′-nitrospiro[cyclopropane-1,3′-indoline]-2′-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5′-nitrospiro[cyclopropane-1,3′-indoline]-2′-one(1399654-82-0)
• EPA Substance Registry System: 5′-nitrospiro[cyclopropane-1,3′-indoline]-2′-one(1399654-82-0)

Safety Data

• Hazardous Substances Data: 1399654-82-0(Hazardous Substances Data)

Upstream product

• 13861-75-1 spiro[cyclopropane-1,3'-indolin]-2'-one 
• 59-48-3 2-oxoindole 
• 20870-79-5 5-nitrooxindole 
• 247129-85-7 (2-bromoethyl)(diphenyl)sulfonium trifluoromethanesulfonate 

Relevant articles and documents

THIENODIAZEPINE DERIVATIVES AND APPLICATION THEREOF

The present invention relates to a class of thienodiazepine derivatives and an application thereof in the preparation of a drug for the treatment of diseases associated with bromodomain and extra-terminal (BET) Bromodomain inhibitors. Specifically, the present invention relates to compounds represented by formulas (I) and (II), as well as pharmaceutically acceptable salts thereof.

Zinc triflate-mediated cyclopropanation of oxindoles with vinyl diphenyl sulfonium triflate: a mild reaction with broad functional group compatibility

The first use of zinc triflate for the cyclopropanation of unprotected oxindoles with vinyl diphenyl sulfonium triflate salt is reported. The reaction proceeded under ambient conditions and consistently provided high yields with broad functional group tolerability. The utility for the late-stage functionalization (LSF) of complex molecules is demonstrated.