1399859-44-9

Basic information

• Product Name: (R)-tert-butyl 4-((R)-2-hydroxy-1-phenylethyl)-3-phenylpiperazine-1-carboxylate
• Synonyms: (R)-tert-butyl 4-((R)-2-hydroxy-1-phenylethyl)-3-phenylpiperazine-1-carboxylate
• CAS NO: 1399859-44-9
• Molecular Weight: 382.503
• Mol File: 1399859-44-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-tert-butyl 4-((R)-2-hydroxy-1-phenylethyl)-3-phenylpiperazine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-butyl 4-((R)-2-hydroxy-1-phenylethyl)-3-phenylpiperazine-1-carboxylate(1399859-44-9)
• EPA Substance Registry System: (R)-tert-butyl 4-((R)-2-hydroxy-1-phenylethyl)-3-phenylpiperazine-1-carboxylate(1399859-44-9)

Safety Data

• Hazardous Substances Data: 1399859-44-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 158457-27-3 N-(2-oxo-2-phenylethyl)glycine methyl ester 
• 70-11-1 α-bromoacetophenone 
• 1399859-56-3 (S)-2-phenyl-2-(S)-2-(phenylpiperazin-1-yl)ethanol 

Downstream Products

• 1240584-34-2 (R)-tert-butyl 3-phenylpiperazine-1-carboxylate 

Relevant articles and documents

Stereoselective synthesis of enantiopure N-protected-3-arylpiperazines from keto-esters

An efficient method for a stereoselective synthesis of optically pure N-Boc-3-arylpiperazines has been developed. After optimization of the protecting group strategy and experimental conditions, compounds were obtained via a highly stereoselective synthesis in up to 45% overall yield. This is a practical route to optically pure piperazines for medicinal chemistry.