139988-32-2

Upstream product

• 10130-89-9 p-carboxyphenylsulfonyl chloride 
• 139988-18-4 N-(9-amino-1,2-dihydro-1-oxobenzo[f]quinazolin-3-yl)pivalamide 

Downstream Products

• 139988-34-4 diethyl N-(4-(((3-amino-1,2-dihydro-1-oxobenzo[f]quinazolin-9-yl)amino)-sulfonyl)benzoyl)-L-glutamate 
• 139987-93-2 4-(((3-amino-1,2-dihydro-1-oxobenzo[f]quinazolin-9-yl)amino)-sulfonyl)benzoic acid 
• 139988-31-1 methyl 4-(((3-amino-1,2-dihydro-1-oxobenzo[f]quinazolin-9-yl)amino)-sulfonyl)benzoate 

Relevant academic research and scientific papers

Benzoquinazoline Inhibitors of Thymidylate Synthase: Enzyme Inhibitory Activity and Cytotoxicity of Some Sulfonamidobenzoylglutamate and Related Derivatives

Several folate-like thymidylate synthase inhibitors are described in which the pteridine nucleus of the folic acid molecule is replaced by a benzoquinazoline moiety, which in turn is attached to the benzoylglutamate side chain by a sulfonamide link.The mo