140-63-6

Basic information

• Product Name: propamidine isetionate
• Synonyms: Propamidine isethionate; M + B 782; M&B 782; Propamidine diisethionate; Propamidine isthionate; Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-(trimethylenedioxy)dibenzamidine (2:1); Propamidine isetionate
• CAS NO: 140-63-6
• Molecular Formula: C₁₇H₂₀N₄O₂?2C₂H₆O₄S
• Molecular Weight: 564.634
• EINECS: 205-423-6
• Mol File: 140-63-6.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: propamidine isetionate(CAS DataBase Reference)
• NIST Chemistry Reference: propamidine isetionate(140-63-6)
• EPA Substance Registry System: propamidine isetionate(140-63-6)

Safety Data

• Hazardous Substances Data: 140-63-6(Hazardous Substances Data)

Usage

Description

Propamidine isethionate is a synthetic diamidine compound that is recognized for its potent antimicrobial properties. It is widely utilized for its antiseptic and disinfectant capabilities, particularly in the management of skin and eye infections such as blepharitis and conjunctivitis. propamidine isetionate exerts its action by disrupting the DNA of the infecting bacterial cells, thereby inhibiting their ability to reproduce and halting the progression of infection. While it is generally considered safe for topical application, caution is advised as systemic absorption may lead to adverse effects, necessitating the need for medical oversight during its use.

Uses

Used in Pharmaceutical Industry:
Propamidine isethionate is used as an antiseptic agent for the treatment of skin and eye infections, such as blepharitis and conjunctivitis. It functions by interfering with the DNA of infecting bacterial cells, preventing their replication and curbing the spread of infection.
Used in Ophthalmology:
In the field of ophthalmology, propamidine isethionate is used as a disinfectant in the form of eye drops. It is particularly effective in treating conjunctivitis, a common eye infection, by inhibiting bacterial growth and reducing inflammation.
Used in Dermatology:
In dermatology, propamidine isethionate is employed as a topical antiseptic for the management of skin infections. It is often formulated in ointments or creams to provide a targeted treatment, ensuring the delivery of the active compound directly to the site of infection.
Used in Antimicrobial Research:
Propamidine isethionate is also utilized in antimicrobial research as a model compound to study the mechanisms of action of diamidine compounds. This research contributes to the development of new antimicrobial agents and a better understanding of bacterial resistance patterns.