1400220-51-0 Usage
General Description
The chemical 2-(3-Bromo-2-fluoro-phenyl)-4,4,5,5-tetramethyl [1,3,2] dioxaborolane is an organoborane compound with the molecular formula C12H15BBrFO2. It is a boron-containing compound that contains a boron-oxygen heterocycle, making it useful in organic synthesis. This chemical is commonly used in palladium-catalyzed cross-coupling reactions, particularly in the formation of carbon-carbon bonds. The presence of the boron atom allows for the efficient transfer of the aryl group to various organic substrates, making it an important reagent in organic chemistry. Additionally, the tetramethyl substitution on the boron atom provides steric hindrance and enhances the stability and reactivity of the compound.
Check Digit Verification of cas no
The CAS Registry Mumber 1400220-51-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,0,2,2 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1400220-51:
(9*1)+(8*4)+(7*0)+(6*0)+(5*2)+(4*2)+(3*0)+(2*5)+(1*1)=70
70 % 10 = 0
So 1400220-51-0 is a valid CAS Registry Number.
1400220-51-0Relevant articles and documents
Ligand-Enabled, Iridium-Catalyzed ortho-Borylation of Fluoroarenes
Kuleshova, Olena,Asako, Sobi,Ilies, Laurean
, p. 5968 - 5973 (2021/05/31)
A terpyridine derivative and an iridium complex catalyze the C-H borylation of a stoichiometric amount of a fluoroarene with high ortho-selectivity and tolerance of functional groups such as bromide, chloride, ester, ketone, amine, and in situ-borylated hydroxyl. Complex drug molecules such as haloperidol can be selectively borylated ortho to the F atom. The terpyridine ligand undergoes rollover cyclometalation to produce an N,N,C-coordinated iridium complex, which may either selectively borylate the fluoroarene by itself or undergo reductive elimination to produce a borylated ligand.
