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tert-butyl 6-(2-methoxypyridin-3-ylamino)-2-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1400284-65-2

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1400284-65-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1400284-65-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,0,2,8 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1400284-65:
(9*1)+(8*4)+(7*0)+(6*0)+(5*2)+(4*8)+(3*4)+(2*6)+(1*5)=112
112 % 10 = 2
So 1400284-65-2 is a valid CAS Registry Number.

1400284-65-2Downstream Products

1400284-65-2Relevant academic research and scientific papers

PYRROLOPYRIDINEAMINO DERIVATIVES AS MPS1 INHIBITORS

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Paragraph 0787-0790, (2014/02/15)

The present invention relates to the use of certain pyrrolopyridineamino derivatives (hereinafter referred to as “PPA derivatives”), particularly 1H-pyrrolo[3,2-c]pyridine-6-amino derivatives, to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps kinase itself. In particular, the present invention relates to PPA derivatives for use as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of the PPA derivatives, and pharmaceutical compositions comprising them. Formula (I)

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