14006-84-9Relevant academic research and scientific papers
One-pot synthesis of polysubstituted 3-acylpyrroles by cooperative catalysis
Cui, Hai-Lei,Tanaka, Fujie
supporting information, p. 5822 - 5826 (2014/08/05)
One-pot syntheses of polysubstituted 3-acylpyrroles from readily available unsaturated ketones and N-substituted propargylated amines have been developed. An aza-Michael/alkyne carbocyclization cascade, by cooperative catalysis using pyrrolidine and a copper salt, followed by oxidation in situ gave 3-acylpyrroles, which were also transformed further to functionalized, highly substituted 3-acylpyrroles. This journal is the Partner Organisations 2014.
Thiopyrano[2,3-e]indol-2-ones: Angelicin heteroanalogues with potent photoantiproliferative activity
Barraja, Paola,Diana, Patrizia,Montalbano, Alessandra,Carbone, Anna,Cirrincione, Girolamo,Viola, Giampietro,Salvador, Alessia,Vedaldi, Daniela,Dall'Acqua, Francesco
experimental part, p. 9668 - 9683 (2009/04/06)
A new class of compounds, the thiopyrano[2,3-e]indol-2-ones, bioisosters of the angular furocoumarin angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents. In particular 7,8-dimethyl-thiopyranoindolone 6c s showed a remarka
Synthesis of pyrroles with fused carbocycles or heterocycles from Weinreb N-vinyl-α-amino amides
Calvo, Luis,Gonzalez-Ortega, Alfonso,Navarro, Rodrigo,Perez, Monica,Sanudo, Maria Carmen
, p. 3152 - 3158 (2007/10/03)
Pyrroles fused to diverse carbocycles and heterocycles were prepared from Weinreb N-vinyl-α-amino carboxamides integrated in cyclic systems. The selective reaction of the carboxamide group with organometallic compounds allowed us to obtain a great variety
