1400634-67-4Relevant academic research and scientific papers
Selective synthesis of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl) formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-substituted-5-aminopyrazoles with new Vilsmeier-type reagents
Chang, Chun-Hsi,Tsai, Henry J.,Huang, Yu-Ying,Lin, Hui-Yi,Wang, Li-Ya,Wu, Tian-Shung,Wong, Fung Fuh
supporting information, p. 1378 - 1386 (2013/02/23)
Various halomethyleniminium salts as novel Vilsmeier agents were synthesized from formamide or N-methylformamide with POCl3. Treatment of N-1-substituted-aminopyrazoles including N-1-phenyl-5-aminopyrazoles, N-1-(2-pyridinyl)-5-aminopyrazoles,
Evaluation of electrophilic heteroaromatic substitution: Synthesis of heteroaromatic-fused pyrimidine derivatives via sequential three-component heterocyclization
Wong, Fung Fuh,Huang, Yu-Ying,Chang, Chun-Hsi
, p. 8492 - 8500 (2012/11/07)
A new sequential three-component heterocyclization was developed by reacting aromatic and heterocyclic substrates, including aminobenzenes, 1-aminonaphthalene, 2-aminopyrazines, 5-aminopyrazoles, 3-aminopyridine, 5-aminopyrimidine, 5-aminoquinoline, and 8
One-pot synthesis and antiproliferative evaluation of pyrazolo[3,4-d] pyrimidine derivatives
Huang, Yu-Ying,Wang, Li-Ya,Chang, Chun-Hsi,Kuo, Yueh-Hsiung,Kaneko, Kimiyoshi,Takayama, Hiroyuki,Kimura, Masayuki,Juang, Shin-Hun,Wong, Fung Fuh
supporting information, p. 9658 - 9664 (2012/11/07)
An efficient one-pot methodology for the synthesis of pyrazolo[3,4-d] pyrimidines was developed by using 5-aminopyrazoles with formamide in presence of PBr3 as the coupling agent. Among the examples presented in this work, compounds 41 and 54-5
