1400666-23-0Relevant academic research and scientific papers
Aerobic palladium(II)-catalyzed dehydrogenation of cyclohexene-1-carbonyl indole amides: An indole-directed aromatization
Kandukuri, Sandeep R.,Oestreich, Martin
, p. 8750 - 8755 (2012/11/07)
A palladium(II)-catalyzed oxidative dehydrogenation of cyclohexene-1- carbonyl indole amides yielding the corresponding benzoylindoles is reported. The new aromatization is also applied to functionalized indoles such as tryptamine and tryptophan. The tethered indole is likely acting as a directing group for allylic C-H bond activation, and there is evidence for a mechanism proceeding through 1,3-diene formation followed by aromatization.
