1400683-01-3

Downstream Products

• 1400683-30-8 (5R)-5-(5-(3-chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ylamino)-2-fluorophenyl)-6,6-difluoro-5-methyl-1,4-oxazepan-3-one 
• 1400683-29-5 (R)-5-(5-amino-2-fluorophenyl)-6,6-difluoro-5-methyl-1,4-oxazepan-3-one 
• 1400683-02-4 (R)-5-[5-((R)-3-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine-7-ylamino)-2-fluoro-phenyl]-6,6-difluoro-5-methyl-[1,4]oxazepane-3-thione 
• 1400683-03-5 (R)-5-[5-((S)-3-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine-7-ylamino)-2-fluoro-phenyl]-6,6-difluoro-5-methyl-[1,4]oxazepane-3-thione 
• 1400682-69-0 [3-((R)-3-amino-6,6-difluoro-5-methyl-2,5,6,7-tetrahydro-[1,4]oxazepin-5-yl)-4-fluoro-phenyl]-((S)-3-chloro-6,7-dihydro-5H-[1]pyrindin-7-yl)-amine 
• 1400683-08-0 (R)-7-(3-((R)-6,6-difluoro-5,7,7-trimethyl-3-thioxo-1,4-oxazepan-5-yl)-4-fluorophenylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile 
• 1400683-07-9 (S)-7-[3-((R)-6,6-difluoro-5,7,7-trimethyl-3-thioxo-[1,4]oxazepan-5-yl)-4-fluoro-phenylamino]-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile 

Relevant academic research and scientific papers

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

The present invention relates to 1,4-Oxazepines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the pres

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

The present invention relates to 1,4-Oxazepines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the pres