1400693-03-9Relevant academic research and scientific papers
Functionalization of 3-chlorobenzaldehyde
Aksjonova, Kristine,Belyakov, Sergey,Liepinsh, Edvards,Boman, Arne,Lundstedt, Torbjorn,Lek, Per,Trapencieris, Peteris
experimental part, p. 2200 - 2208 (2012/09/22)
2-Substituted 3-chlorobenzaldehydes were prepared from the corresponding 2-(3-chlorophenyl)-1,3-dioxolanes using an ortho-lithiation strategy. The 6-chloro-2-formylbenzamide exists only in a ring form, but 6-chloro-2- formylbenzoic acid esters were isolated in both forms as open chain and cyclic tautomers. 7-Chloro-3-hydroxy-3H-isobenzofuran-1-one reacted with nucleophilic reagents at the carbonyl or quaternary carbon depending on the character of nucleophile. Georg Thieme Verlag Stuttgart New York.
