1400744-47-9

Upstream product

• 103676-94-4 4-chloro-6-methoxy-2H-1-benzopyran-2-one 
• 531-59-9 7-methoxycoumarin 
• 95-47-6 o-xylene 

Relevant academic research and scientific papers

A highly active and general catalyst for the stille coupling reaction of unreactive aryl, heteroaryl, and vinyl chlorides under mild conditions

A β-diketiminatophosphane-palladium complex was found to act as an efficient and general catalyst in the Stille coupling reaction of various aryl and heteroaryl chlorides with organostannanes. The results show that this catalytic system allows for the use of less reactive substrates such as deactivated or sterically hindered aryl chlorides. A catalyst loading of 0.5 mol% was sufficient to achieve excellent performance under relatively mild reaction conditions. Furthermore, the scope of catalyst was extended to the coupling of vinyl chlorides. Copyright

Regioselective palladium-catalyzed direct cross-coupling of coumarins with simple arenes

An efficient method for the C4-regiocontrolled C-H functionalization of coumarins to enable facile oxidative cross-couplings with simple arene components is disclosed.