1400796-52-2

Upstream product

• 99-04-7 m-Toluic acid 
• 3245-38-3 methyl deoxycholate 
• 83-44-3 Deoxycholic acid 
• 13050-47-0 3-methylbenzoyl hydrazine 
• 120-33-2 ethyl 3-methylbenzoate 
• 105576-60-1 4-amino-2,4-dihydro-5-(3-methylphenyl)-3H-1,2,4-triazole-3-thione 
• 221876-72-8 methyl 3α-chloroacetoxy-12α-hydroxycholanate 

Relevant academic research and scientific papers

Synthesis using microwave irradiation, characterisation and antibacterial activity of Novel deoxycholic acid-triazole conjugates

Novel deoxycholic acid 3α-triazole conjugates based on methyl 3α-chloroacetoxy-12α-hydroxy-cholanate have been synthesised. The synthesis is accelerated by microwave irradiation under solvent free conditions in the presence of K2CO3. Some of these compounds were tested for antibacterial activity against B.subtilis, P.aeruginosa and S.aureus. The preliminary results indicated that these deoxycholic acid-triazole conjugates have good inhibitory effect against B.subtilis. All of the compounds were characterised by 1H NMR, IR, ESI-MS spectra and elemental analyses.