1400796-75-9

Upstream product

• 99-73-0 para-bromophenacyl bromide 
• 120-80-9 benzene-1,2-diol 
• 1400797-08-1 (S)-4-(2,3-dihydro-benzo[1,4]dioxin-2-yl)-benzaldehyde 
• 1400797-03-6 C₁₆H₁₃BrO₄ 
• 1400797-04-7 C₁₆H₁₅BrO₄ 
• 1400797-05-8 C₁₄H₁₃BrO₃ 
• 1400797-06-9 (S)-2-(4-bromophenyl)-2,3-dihydrobenzo[b][1,4]dioxine 
• 1400797-07-0 C₁₅H₁₁NO₂ 
• 1454648-76-0 C₁₅H₁₂INO₂ 
• 1454648-75-9 C₁₅H₁₀INO₂ 
• 20099-89-2 4-Cyanophenacyl bromide 
• 533-58-4 2-Iodophenol 

Downstream Products

• 1400796-77-1 N-{1-[(S)-4-(2,3-dihydro-benzo[1,4]dioxin-2-yl)-benzyl]-piperidin-4-yl}-2-hydroxy-acetamide trifluoroacetate 
• 1400797-39-8 3-chloro-propane-1-sulfonic acid {1-[(S)-4-(2,3-dihydro-benzo[1,4]dioxin-2-yl)-benzyl]-piperidin-4-yl}-amide 
• 1400796-83-9 1-[(S)-4-(2,3-dihydro-benzo[1,4]dioxin-2-yl)-benzyl]-4-(1,1-dioxo-1λ⁶-isothiazolidin-2-yl)-piperidine 
• 1400796-78-2 N-(1-{4-[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]benzyl}piperidin-4-yl)-2-methoxyacetamide 

Relevant academic research and scientific papers

BENZODIOXANES FOR INHIBITING LEUKOTRIENE PRODUCTION

The present invention relates to compounds of formula (I) wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.

BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present inven