1400796-87-3

Upstream product

• 1126-09-6 4-carbethoxypiperidine 
• 1400797-41-2 (S)-2-[4-(1-bromo-ethyl)-phenyl]-2,3-dihydro-benzo[1,4]dioxine 
• 76-05-1 trifluoroacetic acid 
• 1400797-12-7 (±)-4-(2,3-dihydro-benzo[1,4]dioxin-2-yl)-benzaldehyde 
• 1454648-76-0 C₁₅H₁₂INO₂ 
• 1454648-75-9 C₁₅H₁₀INO₂ 
• 20099-89-2 4-Cyanophenacyl bromide 
• 533-58-4 2-Iodophenol 
• 1400797-40-1 1-[(S)-4-(2,3-dihydro-benzo[1,4]dioxin-2-yl)-phenyl]-ethanol 
• 1400797-07-0 C₁₅H₁₁NO₂ 
• 1400797-06-9 (S)-2-(4-bromophenyl)-2,3-dihydrobenzo[b][1,4]dioxine 
• 1400797-05-8 C₁₄H₁₃BrO₃ 
• 1400797-04-7 C₁₆H₁₅BrO₄ 
• 1400797-08-1 (S)-4-(2,3-dihydro-benzo[1,4]dioxin-2-yl)-benzaldehyde 

Relevant academic research and scientific papers

BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION FOR COMBINATION THERAPY

The present invention relates to a combination comprising compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein, and an additional active agent. The present invention also relates to pharmaceutical compositions comprising these combinations, and methods of using these combinations to treat various diseases and disorders.

BENZODIOXANES FOR INHIBITING LEUKOTRIENE PRODUCTION

The present invention relates to compounds of formula (I) wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.

BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present inven