1400809-84-8

Basic information

• Product Name: (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid
• Synonyms: (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid;(4'-Butyl-3-fluoro-[1,1'-biphenyl]-4-yl)boronic acid
• CAS NO: 1400809-84-8
• Molecular Formula: C16H18BFO2
• Molecular Weight: 272.1223232
• Mol File: 1400809-84-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 424.2±55.0 °C(Predicted)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.40±0.58(Predicted)
• CAS DataBase Reference: (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid(1400809-84-8)
• EPA Substance Registry System: (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid(1400809-84-8)

Safety Data

• Hazardous Substances Data: 1400809-84-8(Hazardous Substances Data)

Usage

Description

(3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid is a chemical compound that plays a significant role in organic synthesis and medicinal chemistry. It features a boronic acid group attached to a biphenyl molecule, with a fluoro and butyl substitution. (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid is recognized for its ability to form reversible covalent bonds with diols and is instrumental in Suzuki-Miyaura coupling reactions for carbon-carbon bond formation. The presence of fluoro and butyl substituents endows it with unique chemical and physical properties, making it a valuable asset in the development of pharmaceuticals and complex organic molecules.

Uses

Used in Organic Synthesis:
(3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid is used as a building block for creating complex organic molecules, particularly in the development of pharmaceuticals. Its unique structure and functional groups contribute to the synthesis of a wide range of organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid is utilized for the development of new pharmaceuticals. Its ability to form reversible covalent bonds with diols and participate in Suzuki-Miyaura coupling reactions allows for the creation of diverse and effective drug candidates.
Used in Suzuki-Miyaura Coupling Reactions:
(3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid is employed as a key component in Suzuki-Miyaura coupling reactions, which are widely used for the formation of carbon-carbon bonds. This reaction is crucial in the synthesis of various organic compounds, including pharmaceuticals and other bioactive molecules.
Used in Drug Discovery:
In the process of drug discovery, (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid serves as a valuable chemical tool. Its unique properties and reactivity make it an ideal candidate for the development of novel drug molecules with potential therapeutic applications.
Overall, (3-Fluoro-4'-butyl[1,1'-biphenyl]-4-yl)boronic acid is a versatile and essential compound in the fields of organic synthesis, medicinal chemistry, and drug discovery, thanks to its unique structure, reactivity, and ability to form reversible covalent bonds.