1400908-44-2Relevant academic research and scientific papers
Studies toward oxyacetamide-linked RNA analogues: Synthesis and conformation of a modified dinucleoside
Jabgunde, Amit M.,Yeole, Sachin D.,Sanap, Shrihari P.,Gadre, Shridhar R.,Dhavale, Dilip D.
, p. 2277 - 2286 (2012/10/07)
A new oxyacetamide-modified dinucleoside with 5-(S) chirality, a hydrophobic 5-C-(2-methoxyethyl) group, and a 2-O-methyl group was synthesized from d-glucose. This dinucleoside showed a helical structure based on CD and NMR spectroscopy. The sugar puckering at the 5 and 3 ends were found to be S'- and N'-types, respectively. These results were substantiated by ab initio density functional theory. Georg Thieme Verlag Stuttgart New York.
