1400997-93-4

Upstream product

• 358627-33-5 N,N-dimethyl-2,3-dihydro-1H-indole-(2S)-2-carboxamide 
• 358627-39-1 tert-butyl (2S)-2-(dimethylcarbamoyl)indoline-1-carboxylate 
• 79815-20-6 (S)-indoline-2-carboxylic acid 
• 144069-67-0 (S)-N-tert-butoxycarbonylindoline-2-carboxylic acid 
• 1400928-44-0 8-phenyl-3-azabicyclo[3.2.1]octane 
• 481000-93-5 1-acryloyl-N,N-dimethyl-2,3-dihydro-1H-indole-(2S)-2-carboxamide 

Downstream Products

• 1400997-94-5 N,N-dimethyl-1-[3-(8-phenyl-3-azabicyclo[3.2.1]oct-3-yl)propanoyl]indoline-(2S)-2-carboxamide monocitrate 

Relevant academic research and scientific papers

Discovery of 1-(β-amino substituted-β-alanyl)-N,N- dimethylindoline-2-carboxamides as novel nonpeptide antagonists of nociceptin/orphanin FQ receptor: Efficient design, synthesis, and structure-activity relationship studies

Since the discovery of endogenous nociceptin/orphanin FQ (N/OFQ) peptide and N/OFQ peptide (NOP) receptor [or opioid-receptor-like-1 (ORL1) receptor], the structures, distribution, and pharmacology have been reported in detail. N/OFQ and NOP receptor are