1401066-08-7

Upstream product

• 1401066-02-1 methyl 1'-(4-methoxybenzyl)-3'-methyl-2',5'-dioxo-5,7-dihydrospiro[cyclopenta[b]pyridine-6,4'-imidazolidine]-3-carboxylate 
• 1401066-01-0 3-bromo-1'-(4-methoxybenzyl)-3'-methyl-5,7-dihydro-2'H,5'H-spiro[cyclopenta[b]pyridine-6,4'-imidazolidine]-2',5'-dione 
• 1401066-00-9 3-(4-methoxybenzyl)-1-methylimidazolidine-2,4-dione 
• 1356330-71-6 5-bromo-2,3-bis(hydroxymethyl)pyridine 
• 824-94-2 p-methoxybenzyl chloride 

Relevant academic research and scientific papers

PYRIDINE CGRP RECEPTOR ANTAGONISTS

The present invention is directed to pyridine derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

PIPERIDINONE CARBOXAMIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS

The present invention is directed to piperidinone carboxamide spirohydantoin derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.