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Upstream product

• 120-72-9 indole 
• 92850-22-1 1-(4-methylphenyl)-2-(phenylamino)ethanone 
• 62-53-3 aniline 
• 619-41-0 4-(bromoacetyl)toluene 

Relevant academic research and scientific papers

Iron-catalyzed direct α-arylation of α-amino carbonyl compounds with indoles

A mild and general α-arylation of α-amino carbonyls with indoles catalyzed by Fe(ClO4)3 has been developed. C-H activation is smoothly fulfilled by using TBHP as the oxidant with good yields. Two hydrogen dissociations make this transformation more environmentally benign because of high atom efficiency.

Direct α-arylation of α-amino carbonyl compounds with indoles using visible light photoredox catalysis

A general and mild method for the construction of functionalized 2-(1H-indol-3-yl)-2-amino-carbonyl compounds was achieved, which represents the first example of direct α-arylation of α-amino carbonyl compounds with indoles using the visible light photoredox catalysis strategy.