1401082-92-5Relevant academic research and scientific papers
2 3 accessing enantiopure endocyclic sulfoximines through 4 catalytic cycloisomerization of oxygenated propargyl-5 6 sulfinamides 7
Cividino, Pascale,Verrier, Charlie,Philouze, Christian,Carret, Sébastien,Poisson, Jean-Fran?ois
, p. 1236 - 1240 (2019)
In this study, a novel strategy to access endocyclic sulfoximines in an enantiopure form is reported. The approach is based on a silver nitrate-catalyzed cyclo-isomerization reaction of oxygenated propargylic sulfinamides and provides efficiently 5-membered endocyclic sulfoximines (isothiazole 1-oxide). These new heterocyclic scaffolds can be isolated or directly converted into cyclic sulfinamides via Lewis acid-mediated sulfur deal-kylation reactions.
Highly diastereoselective addition of alkoxyethynyl aluminium reagents to N-tert-butylsulfinyl aldimines
Verrier, Charlie,Carret, Sebastien,Poisson, Jean-Francois
supporting information, p. 1875 - 1878 (2014/03/21)
The addition of dimethylaluminium alkoxyacetylides to Ellman's sulfinylimines is described. The reaction proceeds with excellent diastereoselectivity and high yield to produce oxygenated propargylamines in one step starting from simple dichloroenol ethers
