1401236-98-3Relevant articles and documents
Unified approach to catechin hetero-oligomers: First total synthesis of trimer EZ-EG-CA isolated from Ziziphus jujuba
Yano, Takahisa,Ohmori, Ken,Takahashi, Haruko,Kusumi, Takenori,Suzuki, Keisuke
, p. 7685 - 7688 (2013/04/23)
A catechin hetero-trimer isolated from Ziziphus jujuba has been synthesized. Among three constituent monomers, (-)-epiafzelechin and (-)-epigallocatechin were prepared by de novo synthesis. Trimer formation relied on the unified approach to oligomers based on the bromo-capping and the orthogonal activation, reaching the reported structure of the natural product. The Royal Society of Chemistry 2012.