1401243-47-7Relevant academic research and scientific papers
Syntheses and evaluation of anti-inflammatory, analgesic and ulcerogenic activities of 1,3,4-oxadiazole and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole derivatives
Chawla, Gita,Kumar, Umesh,Bawa, Sandhya,Kumar, Jagdish
, p. 658 - 665,8 (2012)
Several 2,5-disubstituted-1,3,4-oxadiazoles (4af) and 3,6-disubstituted-1, 2,4-triazolo[3,4-b]-1,3,4-thiadiazoles (7af) were synthesized and characterized by elemental analyses and spectral data. These compounds were screened for their anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation activities. Compound 7c showed excellent anti-inflammatory and remarkable analgesic activity with reduced ulcerogenic and lipid peroxidation activity when compared with ibuprofen.
