1401252-71-8

Basic information

• Product Name: 3-(3-chlorophenylureido)carbonyl-N₁-ethyl-6-hydroxy-4-oxo-pyrido[2,3-h]quinoline
• CAS NO: 1401252-71-8
• Molecular Weight: 436.854
• Mol File: 1401252-71-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-chlorophenylureido)carbonyl-N₁-ethyl-6-hydroxy-4-oxo-pyrido[2,3-h]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-chlorophenylureido)carbonyl-N₁-ethyl-6-hydroxy-4-oxo-pyrido[2,3-h]quinoline(1401252-71-8)
• EPA Substance Registry System: 3-(3-chlorophenylureido)carbonyl-N₁-ethyl-6-hydroxy-4-oxo-pyrido[2,3-h]quinoline(1401252-71-8)

Safety Data

• Hazardous Substances Data: 1401252-71-8(Hazardous Substances Data)

Upstream product

• 1401252-68-3 N-ethyl-6-hydroxy-4-oxo-pyrido[2,3-h]quinoline-3-carboxylic acid 
• 1967-27-7 (3-chlorophenyl)urea 
• 1401252-67-2 C₁₇H₁₆N₂O₄ 

Relevant articles and documents

Synthesis, characterization and microbial assay of new pyridoquinolone-3- carboxamides

The ethyl pyrido[2,3-h]quinolone carboxamides 7-31 have been synthesized and their ability to inhibit Gram positive strains B. subtilis and S. aureus and Gram negative strains E. coli and P. aeruginosa have been tested. Only carboxamides with piperazine derivatives attached at C-3 position show good antibacterial potency compared to standard ciprofloxacin and gatifloxacin. Piperazine derivatives attached at C-3 position of N-ethyl pyrido quinolone increase the activity of their parent compound acid 6, whereas aryl urea attached at this position decrease the antibacterial activity.