1401318-10-2Relevant academic research and scientific papers
Synthetic and structural exploration of [24]Tetrathiacalix[2] arene[2]pyrimidines
Sonawane, Mahendra P.,Thomas, Joice,Dehaen, Wim,Van Rossom, Wim,Van Hecke, Kristof,Jacobs, Jeroen,Van Meervelt, Luc
, p. 8444 - 8450,7 (2012)
A novel class of two atom bridged metacyclophanes-[24] thiacalix[2]arene[2]pyrimidines-has been synthesized via a straightforward SNAr reaction. The conformational properties and intra-annular dimensions of the [24]thiacalix[2]arene[2]pyrimidines were evaluated by X-ray structure analysis and compared with known homothia- and thiacalixarenes. Post-macrocyclization oxidation of the bridging sulfur moieties resulted in a [24]sulfonylcalix[2]arene[2]pyrimidine, which gave access to an unexplored cavity size among sulfonylcalixarenes.
Preorganization in bistriazolyl anion receptors
Merckx, Tamara,Verwilst, Peter,Dehaen, Wim
supporting information, p. 4237 - 4240 (2013/07/26)
A series of 4,6-bis-(1,2,3-triazolyl)-pyrimidine and 4,6-bis-(1,2,3- triazolyl)-pyridine anion receptors were synthesized and the effect of the pyrimidine and pyridine moieties on their binding properties was examined. We found that intramolecular interactions preorganize the 4,6-bis-(1,2,3-triazolyl) -pyridine receptors resulting in higher anion binding constants in comparison with the nonpreorganized 4,6-bis-(1,2,3-triazolyl)-pyrimidine receptor.
