1401320-18-0

Basic information

• Product Name: C₂₁H₂₀O₁₁
• CAS NO: 1401320-18-0
• Molecular Weight: 448.383
• Mol File: 1401320-18-0.mol

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₀O₁₁(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₀O₁₁(1401320-18-0)
• EPA Substance Registry System: C₂₁H₂₀O₁₁(1401320-18-0)

Safety Data

• Hazardous Substances Data: 1401320-18-0(Hazardous Substances Data)

Upstream product

• 33507-92-5 7-(benzyloxy)-5,6-diacetoxy-2-(4-acetoxyphenyl)-4H-chromen-4-one 
• 27740-01-8 scutellarin 

Relevant articles and documents

Design, synthesis and biological evaluation of glucose-containing scutellarein derivatives as neuroprotective agents based on metabolic mechanism of scutellarin in vivo

Based on metabolic mechanism of scutellarin in vivo that scutellarin could be hydrolyzed into scutellarein by β-glucuronide enzyme, some glucose-containing scutellarein derivatives were designed and synthesized through the introduction of glucose moiety at C-7 position of scutellarein via a glucosidic bond. Biological activity evaluation showed that these glucose-containing scutellarein derivatives exhibited potent DPPH radical scavenging activities. Furthermore, the improvement of physicochemical properties such as anticoagulant and neuroprotective activities alongside with the water solubility was achieved by introducing glucose. These findings suggest that the introduction of the glucose moiety to scutellarein wattants further development of this kind of compounds as neuroprotective agents.