1401429-31-9Relevant articles and documents
Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo
Yan, Hong,Teh, Cathleen,Sreejith, Sivaramapanicker,Zhu, Liangliang,Kwok, Anna,Fang, Weiqin,Ma, Xing,Nguyen, Kim Truc,Korzh, Vladimir,Zhao, Yanli
supporting information; experimental part, p. 8373 - 8377 (2012/09/07)
Release me! A new class of photothermal-responsive [2]rotaxane-appended mesoporous silica nanoparticles (MSNPs) was developed. Remote-controlled movement of the α-cyclodextrin ring (green) upon trans-cis isomerization of the azobenzene axle (red) enables the loading and release of drugs on demand (see scheme). Curcumin-loaded MSNPs were shown to release curcumin into zebrafish larvae upon treatment with visible light or heat. Copyright