140166-68-3

Upstream product

• 27835-00-3 ethyl (4-methylbenzoyl)acetate 

Downstream Products

• 193979-41-8 ethyl 6-methyl-2-(4-methyl-phenyl)imidazo[1,2-a]pyridine-3-carboxylate 
• 164460-42-8 2-butyl-4-chloro-5-(hydroxymethyl)-1-<<1-<5-(methoxycarbonyl)-2-methylthiazol-4-yl>-4-phenyl>methyl>-1H-imidazole 
• 164460-43-9 4-[4-(2-Butyl-5-chloro-4-hydroxymethyl-imidazol-1-ylmethyl)-phenyl]-2-methyl-thiazole-5-carboxylic acid methyl ester 
• 164460-34-8 ethyl 4-<4-(bromomethyl)phenyl>-2-methylthiazole-5-carboxylate 
• 887282-93-1 (6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanol 
• 159448-57-4 ethyl 2-methyl-4-(4-methylphenyl)thiazole-5-carboxylate 

Relevant academic research and scientific papers

Molybdenum(VI) dichloride

A novel and efficient method for the one-pot transformation of β-hydroxycarbonyl compounds to a-brominated 1,3-dicarbonyl compounds is achieved with MoO2Cl2 in the presence of N-bromosuccinimide. All the reactions were carried out un

Highly efficient and green synthesis of 2,4-diphenyl substituted thiazoles

2,4-Diphenyl thiazole is an important organic intermediate and its derivatives contain multiple biological properties. In the present study, we reported a new protocol to synthesize 2,4-diphenyl thiazole analogs, which involved the bromination of ethyl benzoylacetates with NBS in the presence of 2-hydroxypropyl-β-cyclodextrin, followed by a direct cyclization with thiobenzamides in water. Compared with the reported method, the current protocol contains less reaction steps, milder reaction conditions, and simpler workup procedure.

Preparation method for 2-halogenated-1,3-dicarbonyl derivative

The invention discloses a preparation method for a 2-halogenated-1,3-dicarbonyl derivative. The preparation method is suitable for wide 1,3-dicarbonyl derivatives. The raw materials are easy to obtain, and multiple varieties are achieved. The product obtained through the method is diversified in type, and can be directly used and used for other further reactions. According to the method, reaction conditions are gentle, the reaction operation and after-treatment process is simple, reaction time is short, the yield is high, pollution is low, and the preparation method is suitable for industrial production.

Nonpeptide Angiotensin II Receptor Antagonists. Synthesis, in Vitro Activity, and Molecular Modeling Studies of N-imidazoles

With the aim of explaining the influence of the structural changes on the biphenylic moiety on the activity, a series of N-imidazoles (I), constructed on the model of DuPont compounds by replacing either the central or terminal pheny

Substituted azoles, a process for their preparation, and their use

The invention relates to compounds of the formula (I) STR1 in which X, Y and Z are identical or different and are N or CR2, and the other radicals have the meaning defined in the description, a process for the preparation thereof, agents contai