1401675-51-1Relevant academic research and scientific papers
One-pot synthesis of 4(3H)-quinazolinones from azides, alkynes, anilines, and carbon monoxide
Shen, Yang,Han, Chao,Cai, Shuying,Lu, Ping,Wang, Yanguang
supporting information, p. 5671 - 5673 (2012/10/29)
A one-pot synthesis of 4(3H)-quinazolinones from terminal alkynes, sulphonyl azide, o-iodoanilines, and carbon monoxide has been developed. This cascade process includes the copper-catalyzed three-component reaction of alkyne, azide and amine, the palladium-catalyzed carbonylation, and the Lewis acid catalyzed hydrolysis of sulfonamide.
