140170-18-9Relevant articles and documents
Synthesis of (+)-obtusenyne
Mak, S.Y. Frankie,Curtis, Neil R.,Payne, Andrew N.,Congreve, Miles S.,Wildsmith, Andrew J.,Francis, Craig L.,Davies, John E.,Pascu, Sofia I.,Burton, Jonathan W.,Holmes, Andrew B.
experimental part, p. 2867 - 2885 (2009/06/17)
An enantioselective synthesis of the halogenated medium-ring ether natural product (+)-obtusenyne is reported which uses the ring expansion of a seven-membered ketene acetal by means of a Claisen rearrangement to construct the core nine-membered oxygen he
A synthesis of (+)-obtusenyne
Frankie Mak,Curtis, Neil R.,Payne, Andrew N.,Congreve, Miles S.,Francis, Craig L.,Burton, Jonathan W.,Holmes, Andrew B.
, p. 3199 - 3201 (2007/10/03)
A synthesis of the halogenated medium-ring ether natural product (+)-obtusenyne is reported utilizing a Claisen rearrangement and an intramolecular hydrosilation as key steps. Georg Thieme Verlag Stuttgart.
Studies towards the synthesis of obtusenyne. Synthesis of the hexahydrooxonin nucleus
Curtis, Neil R.,Holmes, Andrew B.,Looney, Mark G.
, p. 671 - 674 (2007/10/02)
The advanced intermediate (the 2,3,4,7,8,9-hexahydrooxonin) 3 for the synthesis of the Laurencia oxonane natural product, obtusenyne 1 was prepared in 8 steps from the previously reported lactone 4. The key transformations were the stereoselective enolate
