140170-18-9Relevant articles and documents
Synthesis of (+)-obtusenyne
Mak, S.Y. Frankie,Curtis, Neil R.,Payne, Andrew N.,Congreve, Miles S.,Wildsmith, Andrew J.,Francis, Craig L.,Davies, John E.,Pascu, Sofia I.,Burton, Jonathan W.,Holmes, Andrew B.
experimental part, p. 2867 - 2885 (2009/06/17)
An enantioselective synthesis of the halogenated medium-ring ether natural product (+)-obtusenyne is reported which uses the ring expansion of a seven-membered ketene acetal by means of a Claisen rearrangement to construct the core nine-membered oxygen he
Studies towards the synthesis of obtusenyne. Synthesis of the hexahydrooxonin nucleus
Curtis, Neil R.,Holmes, Andrew B.,Looney, Mark G.
, p. 671 - 674 (2007/10/02)
The advanced intermediate (the 2,3,4,7,8,9-hexahydrooxonin) 3 for the synthesis of the Laurencia oxonane natural product, obtusenyne 1 was prepared in 8 steps from the previously reported lactone 4. The key transformations were the stereoselective enolate
