1401719-90-1

Basic information

• Product Name: Cbz-D-Glu(D-Trp-O-CH(CH₃)-O-CO-O-cyclohexyl)-O-Et
• Synonyms: Cbz-D-Glu(D-Trp-O-CH(CH₃)-O-CO-O-cyclohexyl)-O-Et
• CAS NO: 1401719-90-1
• Molecular Weight: 665.741
• Mol File: 1401719-90-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cbz-D-Glu(D-Trp-O-CH(CH₃)-O-CO-O-cyclohexyl)-O-Et(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-D-Glu(D-Trp-O-CH(CH₃)-O-CO-O-cyclohexyl)-O-Et(1401719-90-1)
• EPA Substance Registry System: Cbz-D-Glu(D-Trp-O-CH(CH₃)-O-CO-O-cyclohexyl)-O-Et(1401719-90-1)

Safety Data

• Hazardous Substances Data: 1401719-90-1(Hazardous Substances Data)

Upstream product

• 97996-97-9 α-ethyl D-N-carbobenzoxyglutamate 
• 1382326-14-8 Cbz-D-Glu(D-Trp-OH)-O-Et 
• 99464-83-2 1-chloroethyl cyclohexyl carbonate 

Downstream Products

• 1401719-45-6 H-D-Glu(D-Trp-O-CH(CH₃)-O-CO-O-cyclohexyl)-O-Et hydrochloride 

Relevant articles and documents

PRODRUGS OF D-ISOGLUTAMYL-[D/L]-TRYPTOPHAN

Provided are carboxylic ester derivatives of formula (I), methods of preparing them, and methods for using them. These compounds are prodrugs of D-isoglutamyl-[D/L]-tryptophan. The in vitro bioconversion of some of the prodrugs to the parent drug D-isoglutamyl-D-tryptophan (or thymodepressin) was tested in human hepatocytes and in human blood. In vivo pharmacokinetic studies following oral administration of some of the prodrugs to rats are also reported.