140176-39-2Relevant academic research and scientific papers
Synthesis of Inhibitors of 2,3-Oxidosqualene-lanosterol Cyclase: Conjugate Addition of Organocuprates to N-(Carbobenzyloxy)-3-carbomethoxy-5,6-dihydro-4-pyridone
Dodd, Dharmpal S.,Oehlschlager, Allan C.
, p. 2794 - 2803 (2007/10/02)
Synthesis of ammonium ion analogues of the first cationic intermediate, 5, presumed to be formed during the cyclization of 2,3-oxidosqualene by 2,3-oxidosqualene-lanosterol cyclase are reported.The required 2,3-substituted-4-piperidinols are prepared by c
